Last edited by Kazrakinos
Sunday, August 9, 2020 | History

2 edition of Chemical aspects of polypeptide chain structures and the cyclol theory found in the catalog.

Chemical aspects of polypeptide chain structures and the cyclol theory

Dorothy Wrinch

Chemical aspects of polypeptide chain structures and the cyclol theory

by Dorothy Wrinch

  • 272 Want to read
  • 15 Currently reading

Published by Plenum Press in New York .
Written in English

    Subjects:
  • Polypeptides

  • Edition Notes

    Includes bibliographies.

    Statement[by] Dorothy Wrinch.
    Classifications
    LC ClassificationsQD431 .W695 1965
    The Physical Object
    Pagination195 p.
    Number of Pages195
    ID Numbers
    Open LibraryOL5950416M
    LC Control Number65023068

    Dorothy Wrinch has written: 'Fourier transforms and structure factor' 'Chemical aspects of polypeptide chain structures and the cyclol theory' Asked in Authors, Poets, and Playwrights What has the. The chemical structure of proteins. It also dovetailed quite nicely with the ‘cyclol’ theory of protein structure (see below), which was enjoying popularity at this time. Evidence is adducted in support of the hypothesis that the molecule of natural, soluble protein is not a flexible open chain of polypeptide but has a compact Cited by: 3.

    Diffraction of X-rays by proteins, nucleic acids, and viruses [by] Herbert R. Wilson. Format Book Published New York, St. Martin's Press, Description vi, p. illus. 23 cm. Chemical aspects of polypeptide chain structures and the cyclol theory. 环醇假说(cyclol hypothesis),為第一个折叠的球状蛋白质结构模型概念 ,这是 多萝西林奇 ( 英语 : Dorothy Maud Wrinch ) 在20世纪30年代基于三个假设提出的。 首先,该假设假设两个肽键由Cyclol反应交联而成(图1),这些交联键是共价的肽的同系物之间的氢键,而非“共价键”。.

    Polypeptides analogous to cellulose derivatives (when suitably substituted on the functional groups of the amino acid residues) are able to give rise to anisotropic melts with cholesteric structures. The first reported examples are represented by copolymers of γ-n-alkyl-L-glutamates, as represented by (7). 81 Depending upon the chemical composition, the prepared copolymers form mesophases. In proteins, localized folding of a polypeptide chain into regular structures (i.e., alpha-helix and beta-pleated sheet) stabilized by hydrogen bonding between atoms of the peptide backbone. In nucleic acids, elements of structure (e.g., helices and hairpins) stabilized by hydrogen bonding and hydrophobic interactions between complementary bases.


Share this book
You might also like
Missions at home

Missions at home

Exodus

Exodus

David Moore.

David Moore.

Authentic details of the Valdenses, in Piemont and other countries

Authentic details of the Valdenses, in Piemont and other countries

Expenses of district judges.

Expenses of district judges.

The essential Mengzi

The essential Mengzi

Extending the power of Visual Basic

Extending the power of Visual Basic

wooden horse, poems.

wooden horse, poems.

Weight control.

Weight control.

The alliance between church and state

The alliance between church and state

Tribal nation

Tribal nation

Transition metal hydrides

Transition metal hydrides

Dante, Petrarch, Camoens CXXIV Sonnets

Dante, Petrarch, Camoens CXXIV Sonnets

life and times of a good keen man

life and times of a good keen man

Chemical aspects of polypeptide chain structures and the cyclol theory by Dorothy Wrinch Download PDF EPUB FB2

Chemical aspects of polypeptide chain structures and the cyclol theory [Wrinch, Dorothy] on *FREE* shipping on qualifying offers. Chemical aspects of polypeptide chain structures and the cyclol theoryAuthor: Dorothy Wrinch.

On the nature of the embedding of polypeptide chain fragments in intact peptide structures; The chemical nature of the active sites on enzymic proteins; Chemical events occurring during peptide synthesis and peptide degradation; Polytransitions in biological systems; Studies of cyclol chemical issues by way of model molecules; Growing points in the new picture of polypeptide chain structures.

Additional Physical Format: Online version: Wrinch, Dorothy, Chemical aspects of polypeptide chain structures and the cyclol theory.

New York, Plenum Press, Get this from a library. Chemical aspects of polypeptide chain structures and the cyclol theory. [Dorothy Wrinch]. Author(s): Wrinch,Dorothy, Title(s): Chemical aspects of polypeptide chain structures and the cyclol theory. Country of Publication: United States Publisher: New York, Plenum Press, The cyclol hypothesis stimulated many scientists to research questions in protein structure and chemistry, and was a precursor of the more accurate models hypothesized for the DNA double helix and protein secondary structure.

Wrinch D. Chemical Aspects of Polypeptide Chain Structures and the Cyclol Theory. Plenum Press: New York, Diary entry Rockefeller Foundation Archives, Rockefeller Archive Center. Picture 5: The image shows the polypeptide chains. Image Source: Polypeptide Structure. Polypeptides have four levels of structure and they are the following.

Primary structure. The primary structure is the sequence of amino acid in the polypeptide chain in line with the location of disulfide bonds. The tertiary structure of a polypeptide or protein is the three-dimensional arrangement of the atoms within a single polypeptide chain.

For a polypeptide consisting of a single conformational folding pattern (e.g., an alpha helix only), the secondary and tertiary structure may be one and the same. Chemical Aspects of Polypeptide Chain Structures and the Cyclol Theory, by Dorothy Wrinch (Plenum Press, New York, p.,$).

Google Scholar High Molecular Compounds in Petroleum, by S. Sergienko translated from the Russian second, revised and augmented edition by J. Schmorak (Israel Program for Scientific Translations, Jerusalem.

Cyclol. The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late s, and was based on three assumptions.

Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. Chemical Aspects of Polypeptide Chain Structures and the Cyclol Theory London: Gollancz.

Chemical Aspects of Polypeptide Chain Structures and the Cyclol Theory Author: A. Paton. Her two books, Chemical Aspects of the Structure of Small Peptides, An Introduction published inand the sequel, Chemical Aspects of Polypeptide Chain Structures and the Cyclol Theory published inwere meant to be the culmination of her thirty years of developing and defending her study of proteins.

Wrinch's list of publications eventually included papers and books. Wrinch D. Chemical Aspects of Polypeptide Chain Structures and the Cyclol Theory.

Plenum Press: New York, Lucente G, Romeo A. Synthesis of cyclols from some small peptides via amide-amide reaction. Chem. Commun. ; â Cerrini S, Fedell W, Mazza F.

X -ray crystallographic proof of a cyclol structure in a tripeptide. The order and arrangement of these amino acids in a polypeptide chain will produce different chemical structures. A protein's structure is essential to its function. A Contemporary Picture of the Chemical Aspects of Polypeptide Chain Structures and Certain Problems of Molecular Biology DOROTHY WRINCH 1 Nature volumepages – () Cite this Cited by: 1.

cyclol theory and the polypeptide-chain theory (7). In this paper we analyzed the X-ray evidence, the thermochemical evidence, and several other aspects of the problem. In her article about Dorothy Wrinch Maureen M. Julian mentions that a structure somewhat similar to the one as-pect of the cyclol structure had been found in the ergot alkaloids.

Fourier transforms and structure factors; American Society for X-Ray and Electron Diffraction. ; Chemical aspects of the structure of small peptides; an introduction. Chemical aspects of polypeptide chain structures and the cyclol theory List of Wrinch's philosophy publications.

The main focus of her work, however, was the presentation and defence of her cyclol theory; she doggedly ignored the accumulating evidence against it. Her two books, Chemical Aspects of the Structure of Small Peptides () and Chemical Aspects of Polypeptide Chain Structure and the Cyclol Theory (), presented the history of protein.

In she published her ideas in the book Chemical Aspects of Polypeptide Chain Structure: An introduction. Ironically, Pauling's theory, which involved the alpha helix model, also proved to be wrong. Pauling had based his model on X-ray diffraction data coupled with his experiments, which showed the peptide bond to be two-dimensional.

Chemical aspects of polypeptide chain structures and the cyclol theory / [by] Dorothy Wrinch Wrinch, Dorothy, [ Book: ].Chemical aspects of polypeptide chain structures and the cyclol theory "Selected papers of Dorothy Wrinch, from the Sophia Smith Collection," in "Structures of Matter and Patterns in Science, inspired by the work and life of Dorothy Wrinch, –, The Proceedings of a Symposium held at Smith College, Northampton, Massachusetts Title Sources; Chemical aspects of polypeptide chain structures and the cyclol theory: Fourier transforms and structure factors: Structures of matter and patterns in science: inspired by the work and life of Dorothy Wrinch, the proceedings of a symposium held at Smith College, Northampton, Massachusetts, Septemberand selected papers of Dorothy Wrinch, from the Sophia.